Nutraceutical testing : gut research release the potential of your compounds
Nutraceuticals are increasingly gaining importance as consumers seek natural methods to support their health. These products go beyond basic nutrition, offering benefits for a variety of health conditions. Enterosys provides advanced research in gut health, and our nutraceuticals testing services are designed to assess the safety and efficacy of your compound through rigorous preclinical testing methods.
What are nutraceuticals?
Nutraceuticals are products that provide health benefits, enhancing the overall well-being of consumers. They form a unique category that lies between pharmaceuticals and functional foods. Nutraceuticals are derived from natural sources—either animal or plant-based—and are extracted, concentrated, and formulated for preventive use. These products are designed not only for general wellness but also to prevent certain disorders and can support pharmaceutical treatments.
How nutraceuticals influence the gut microbiota
The human gut microbiota, dominated by Firmicutes and Bacteroidetes phyla, plays a key role in the bioavailability and efficacy of nutraceuticals. Through specific nutraceutical interventions, the diversity and abundance of microbial populations can be modulated, which in turn directly affects gut function. An increase in alpha-diversity (the richness within a microbial community) and beta-diversity (differences between microbial communities) is often associated with better gut health and greater resilience against dysbiosis.
Probiotics and prebiotics are nutraceuticals that target the gut microbiota. Prebiotics serve as nutritional intake for beneficial bacteria, while probiotics introduce live bacteria into the gut. These interventions in the microbial community help reduce gut inflammation through the production of short-chain fatty acids (SCFAs) and the regulation of immune responses.
Nutraceuticals’ impact on the gut-peripheral organs axis
The gut is a central organ, acting as a bridge between nutraceuticals and various physiological systems. Targeting the gut through nutraceuticals allows for significant impacts on not only gastrointestinal disorders but also on distant organs. For instance, gut-targeted interventions can improve metabolic function, reduce neuroinflammation, and improve skin conditions. Understanding the pivotal role of the gut allows nutraceuticals to offer preventive strategies across multiple health indications, including metabolic, neurodegenerative and dermatological disorders.
Why nutraceuticals testing is indispensable
The Importance of Nutraceutical Testing Labs
In today’s competitive market, nutraceutical companies must provide scientific validation for their products. Collaborating with specialised contract research organisations (CROs) like Enterosys offers the necessary scientific proof, enhancing the credibility and marketability of nutraceutical products. This not only builds brand reputation but also ensures product differentiation in a crowded marketplace.
Nutraceuticals testing: what Enterosys offers
At Enterosys, we are experts in digestive physiology and offer tailored testing protocols to maximise the potential of nutraceutical products. Our advanced in vitro and in vivo models enable thorough testing in controlled environments, ensuring the products deliver their intended benefits.
Contact us for nutraceuticals testing services! Our team develop nutraceuticals testing protocols that will highlight the unique benefits of your products and ensure they meet both industry standards and customer expectations.
White paper ENTEROSYS
« GUT IS THE LINK »
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Get inside the head of our co-founder Claude Knauf.
Come discover his background, his key dates, how he got the gut feeling and the link between enteric neurons and glycemic control as well as other health related areas.
OUR KEY SCIENTIFIC FINDINGS ABOUT THE GUT
The gut-brain axis: exploring its role in health care
In the intestine, gut distension and nutrients are detected by mechanoreceptors and chemoreceptors, respectively. The activation of these receptors sends an afferent nervous message to the hypothalamus in the brain. In turn, the hypothalamus controls the glucose entry in tissues, and thus glycemia.
12-HETE enterosyne: new insights into glucose metabolism
The discovery of intestinal actors, such as enterosynes, able to modulate the ENS-induced duodenal contraction is an innovative approach. Among all the intestinal factors, the understanding of the role of gut microbes in controlling glycaemia remains a major target. For instance, we researched and demonstrated how the modulation of gut microbiota by prebiotics could permit the identification of novel enterosynes.
How does the gut microbiota interact with our second brain?
Currently, the gut is considered a primary site for the development of pathologies that modify brain functions such as neurodegenerative (Parkinson’s, Alzheimer’s, etc.) and metabolic (type 2 diabetes, obesity, etc.) disorders. Deciphering the mode of interaction between microbiota and the brain is a real original option to prevent (and maybe treat in the future) the establishment of gut-brain disfunctions and associated pathologies.
Do you have a question about the contribution of gut models in your innovative research ?
Our team of experts will be delighted to answer all of your questions. We guide you in the design of an optimized protocol to meet your objectives and add value to your molecules with quick and concrete solutions.